WebApr 14, 2024 · CircRNA, the latest research hotspot in the field of RNA, is a special non-coding RNA molecule, which is unable to encode proteins and bind polyribosomes. As a regulatory molecule, circRNA participates in cancer cell generation and progression mainly through the mechanism of competitive endogenous RNA. In numerous regulated cancer … WebJan 12, 2024 · We describe an integrated computational pipeline to reliably characterize full-length circRNA isoforms using isoCirc data. Using isoCirc, we generate a comprehensive catalog of 107,147 full-length ...
circRNAs Signature as Potential Diagnostic and Prognostic …
WebMay 11, 2024 · circRNAs are single-stranded circles of RNA, which form highly stable closed loops. circRNAs can have different functions. Among these, the miRNA sponging is the best-characterized role. circRNAs... WebCircular RNA (circRNA) is a newly described type of non-coding RNA. Active research is greatly enriching the current understanding of the expression and role of circRNA, and a large amount of evidence has implicated circRNA in the pathogenesis of certain renal diseases, such as renal cell carcinoma, acute kidney injury, diabetic nephropathy and … greek stuffed chicken breast recipes
Mapping CircRNA–miRNA–mRNA regulatory axis identifies …
WebDec 14, 2024 · CircRNAs exert biological functions by acting as transcriptional regulators, microRNA (miR) sponges and protein templates. Moreover, emerging evidence has revealed that a group of circRNAs can serve as protein decoys, scaffolds and recruiters. However, the existing research on circRNA-protein interactions is quite limited. WebNov 18, 2024 · For example, circRNA binds and decoys RNA binding proteins (RBPs) , and it also facilitates co-localization of enzymes by serving as a protein scaffold . Though circRNAs are considered to be one type of ncRNA, recent studies have confirmed that they can be translated in some cases [22, 23]. WebWe found that while all genes producing circRNAs share gene architecture features common to circRNA host genes, genes producing circRNAs in PARP1 knockdown conditions had … greek stuffed peppers rachael ray