Titin is the largest known protein; its human variant consists of 34,350 amino acids, with the molecular weight of the mature "canonical" isoform of the protein being approximately 3,816,030.05 Da. Its mouse homologue is even larger, comprising 35,213 amino acids with a molecular weight of 3,906,487.6 Da. It … See more Titin /ˈtaɪtɪn/ (contraction for Titan protein) (also called connectin) is a protein that in humans is encoded by the TTN gene. Titin is a giant protein, greater than 1 µm in length, that functions as a molecular spring that is responsible … See more The human gene encoding for titin is located on the long arm of chromosome 2 and contains 363 exons, which together code for 38,138 amino acid residues (4200 kDa). Within the … See more Titin is a large abundant protein of striated muscle. Titin's primary functions are to stabilize the thick filament, center it between the thin filaments, prevent overstretching of the … See more Mutations anywhere within the unusually long sequence of this gene can cause premature stop codons or other defects. Titin mutations are … See more In 1954, Reiji Natori proposed the existence of an elastic structure in muscle fiber to account for the return to the resting state when muscles are stretched and then released. In 1977, Koscak Maruyama and coworkers isolated an elastic protein from … See more The titin domains have evolved from a common ancestor through many gene duplication events. Domain duplication was facilitated by the fact that most domains are encoded by single exons. Other giant sarcomeric proteins made out of Fn3/Ig repeats … See more Titin has been shown to interact with: • ANK1, • ANKRD1, • ANKRD23 See more WebThe molecular masses of proteins, nucleic acids, and other large polymers are often expressed with the units kilodaltons (kDa), megadaltons (MDa), etc. Titin, one of the …
Titin: Quantitative mass measurements by scanning
WebFeb 1, 1997 · The molecular mass of this novel protein, titin 1 (also referred to as connectin 2), was earlier estimated to range between 1.2 and 3.0 MD (for reviews, see References 3 and 4). When the intensity of titin bands on SDS gels is compared with that of other myofibrillar proteins, it appears that titin is, after myosin and actin, the third most ... WebMay 20, 2016 · The molecular mass of titin isoforms (N2A, N2BA and N2B) and their isovariants are 3000–3700 kDa [12,18,19]. ... Protein concentrations were estimated using molar absorption coefficients ... sccm ssl inspection
What is the dimension of molar mass? - Chemistry Stack Exchange
WebIt has a mass 1/4226 that of Saturn, making it the largest moon of the gas giants relative to the mass of its primary. It is second in terms of relative diameter of moons to a gas giant; Titan being 1/22.609 of Saturn's diameter, Triton is larger in diameter relative to Neptune at 1/18.092. [citation needed] WebTitin, is definitely the largest protein in the body, with a molecular weight of 3 million Dalton and composed of 27,000 amino acids. Paradoxically, this huge structure was elusive until … WebIntroduction Titin is the largest protein chain in your body, with more than 34,000 amino acids. This titanic protein acts like a big rubber band in our muscles. It is attached at one … running shoes most cushion